Article
Defective neuronogenesis in the absence of Dlx5.
Molecular and cellular neurosciences - 1 Jan 2004
Perera Marzia, Merlo Giorgio R, Verardo Sara, Paleari Laura, Corte Giorgio, Levi Giovanni
Abstract excerpt
Dlx genes play an important role in the control of the development of the central nervous system (CNS). Single or compound inactivation of Dlx1, Dlx2, or Dlx5 in the mouse causes defects of neuronal migration and differentiation. Dlx5, in particular, is essential for the correct development of the olfactory system. Targeted inactivation of Dlx1 and Dlx2 in the mouse results in abnormal neuronal differentiation in...
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