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Article

SVM based method for predicting HLA-DRB1*0401 binding peptides in an antigen sequence

22 Jan 2004

Abstract excerpt

Abstract Summary: Prediction of peptides binding with MHC class II allele HLA-DRB1*0401 can effectively reduce the number of experiments required for identifying helper T cell epitopes. This paper describes support vector machine (SVM) based method developed for identifying HLA-DRB1*0401 binding peptides in an antigenic sequence. SVM was trained and tested on large and clean data set consisting of 567 binders and...

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PMID: 14960470
DOI: 10.1093/bioinformatics/btg424

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