Article
The quantitative prediction of HLA-B*2705 peptide binding affinities using Support Vector Regression to gain insights into its role for the Spondyloarthropathies.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2015
Uslan Volkan, Seker Huseyin
Abstract excerpt
Computational methods are increasingly utilised in many immunoinformatics problems such as the prediction of binding affinity of peptides. The peptides could provide valuable insight into the drug design and development such as vaccines. Moreover, they can be used to diagnose diseases. The presence of human class I MHC allele HLA-B*2705 is one of the strong hypothesis that would lead spondyloarthropathies. In...
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