The power of the N-test of haplotype concordance.

Abstract excerpt

The N-test of haplotype concordance among siblings affected by some disease under investigation is used to decide whether there is a disease susceptibility gene linked to a marker locus or chromosomal region. The use of this test and appropriate modifications of it is briefly reviewed. The power of the ordinary N-test is then derived as a function of several parameters. The sample size needed to attain a given...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Genetic Linkage
• Share to Genetic Predisposition to Disease