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Article

Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age.

American journal of human genetics - 1 Mar 2004

van Asselt Kristel M, Kok Helen S, Putter Hein, Wijmenga Cisca, Peeters Petra H M, van der Schouw Yvonne T, Grobbee Diederick E, te Velde Egbert R, Mosselman Sietse, Pearson Peter L

Abstract excerpt

Age at natural menopause may be used as parameter for evaluating the rate of ovarian aging. Environmental factors determine only a small part of the large variation in menopausal age. Studies have shown that genetic factors are likely to be involved in variation in menopausal age. To identify quantitative-trait loci for this trait, we performed a genomewide linkage study with age at natural menopause as a...

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Identifiers

PMID: 14872408
DOI: 10.1086/382136
PMCID: PMC1182258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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