Article
No evidence of linkage between the locus for autosomal dominant retinitis pigmentosa and D3S47 (C17) in three Australian families.
Human genetics - 1 Jan 1991
Jiménez J B, Samanns C, Watty A, Pongratz J, Olsson J E, Dickinson P, Buttery R, Gal A, Denton M J
Abstract excerpt
A linkage analysis has been performed on three Australian families segregating for autosomal dominant retinitis pigmentosa (ADRP). No evidence of linkage has been found in any of the pedigrees studied between the locus D3S47 and the gene for ADRP. The D3S47 locus was found to show very close linkage with the ADRP gene in a large Irish pedigree. Our study together with a similar report on a British family...
Topics
- Adolescent
- Adult
- Australia
- Child
- Child, Preschool
- Female
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male