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Article

Selection of resistant mutants of Mycobacterium avium in beige mice by clarithromycin monotherapy.

Antimicrobial agents and chemotherapy - 1 Dec 1992

Ji B, Lounis N, Truffot-Pernot C, Grosset J

Abstract excerpt

Beige mice were inoculated intravenously with 10(7.90) CFU of Mycobacterium avium 101. Among the untreated control mice, when the mean CFU per spleen increased to a level greater than 10(8), small numbers of organisms resistant to clarithromycin (CLARI) were isolated from some of the spleens; the frequency of CLARI-resistant mutants was estimated to be between 10(-8) and 10(-9). In mice treated with 200 mg of...

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Identifiers

PMID: 1482155
DOI: 10.1128/AAC.36.12.2839
PMCID: PMC245555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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