Virulence of antibiotic-resistant Salmonella typhimurium.

doi:10.1073/pnas.95.7.3949

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Article

Virulence of antibiotic-resistant Salmonella typhimurium.

Proceedings of the National Academy of Sciences of the United States of America - 31 Mar 1998

Björkman J, Hughes D, Andersson D I

Abstract excerpt

We show that most Salmonella typhimurium mutants resistant to streptomycin, rifampicin, and nalidixic acid are avirulent in mice. Of seven resistant mutants examined, six were avirulent and one was similar to the wild type in competition experiments in mice. The avirulent-resistant mutants rapidl...

Topics

Animals
Drug Resistance, Microbial
Humans
Mice
Molecular Sequence Data
Mutation
Salmonella Infections, Animal
Salmonella typhimurium
Virulence

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