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Article

Rho activity critically and selectively regulates endothelial cell organization during angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 17 Feb 2004

Hoang Mien V, Whelan Mary C, Senger Donald R

Abstract excerpt

The mechanisms that control organization of endothelial cells (ECs) into new blood vessels are poorly understood. We hypothesized that the GTPase Rho, which regulates cytoskeletal architecture, is important for EC organization during neovascularization. To test this hypothesis, we designed a highly versatile mouse skin model that used vascular endothelial growth factor-expressing cells together with packaging...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14769914
DOI: 10.1073/pnas.0308525100
PMCID: PMC357020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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