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Article

ATF6 modulates SREBP2-mediated lipogenesis.

The EMBO journal - 25 Feb 2004

Zeng Lingfang, Lu Min, Mori Kazutoshi, Luo Shengzhan, Lee Amy S, Zhu Yi, Shyy John Y-J

Abstract excerpt

Activating transcription factor 6 (ATF6) and sterol regulatory element-binding proteins (SREBPs) are activated by proteolytic cleavage. The ensuing nuclear translocation of their N-termini (i.e., ATF6(N) and SREBP(N)) activates the respective target genes involved in unfolded protein response and...

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Source

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Identifiers

PMID: 14765107
DOI: 10.1038/sj.emboj.7600106
PMCID: PMC381012

Genes

ATF6
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14765107-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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