Article
Angiotensin-converting enzyme and alpha-2-macroglobulin gene polymorphisms are not associated with Alzheimer's disease in Colombian patients.
Journal of the neurological sciences - 15 Mar 2004
Camelo Dalila, Arboleda Gonzalo, Yunis Juan J, Pardo Rodrigo, Arango Gabriel, Solano Eugenia, López Luis, Hedmont Daniel, Arboleda Humberto
Abstract excerpt
Polymorphisms in alpha-2-macroglobulin (A2M) and angiotensin-converting enzyme (ACE) genes have been considered as risk factors for Alzheimer's disease (AD) independently of the risk conferred by the apolipoprotein E sigma4 allele (APOEsigma4) in diverse populations. In the present study, we have analysed the distribution of genotypes and alleles of the insertion/deletion (I/D) polymorphisms of ACE and A2M in 83...
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