Article
Angiotensin-converting enzyme I/D polymorphism and arterial wall thickness in a general population. The Vobarno Study.
Circulation - 1 Jun 1995
Castellano M, Muiesan M L, Rizzoni D, Beschi M, Pasini G, Cinelli A, Salvetti M, Porteri E, Bettoni G, Kreutz R
Abstract excerpt
BACKGROUND: It has been reported that the D allele of an insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene is associated with conditions of increased cardiovascular risk, including left ventricular hypertrophy. METHODS AND RESULTS: Considering that a genetically determined overactivity of the renin-angiotensin system may influence cardiac as well as vascular growth, we...
Topics
- Alleles
- Blood Pressure
- Carotid Arteries
- Carotid Artery Diseases
- Cross-Sectional Studies
- Female
- Gene Deletion
- Gene Frequency
- Genotype
- Humans
- Intracranial Arteriosclerosis