Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons.

Journal of neuroscience methods - 15 Feb 2004

Kim Jinhyun, Dittgen Tanjew, Nimmerjahn Axel, Waters Jack, Pawlak Verena, Helmchen Fritjof, Schlesinger Sondra, Seeburg Peter H, Osten Pavel

Abstract excerpt

Sindbis virus-based vectors have been successfully used for transient heterologous protein expression in neurons. Their main limitation arises from infection-associated cytotoxicity, attributed largely to a progressive shut down of host cell protein synthesis. Here we evaluated a modified Sindbis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoradiography
Share to Cysteine Endopeptidases
Share to Gene Expression Regulation, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Transfer Techniques

Share to Membrane Potentials

Share to Neural Conduction

Share to Phosphopyruvate Hydratase

Share to Sindbis Virus

Source

Identifiers

PMID: 14757348
DOI: 10.1016/j.jneumeth.2003.09.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14757348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sindbis vector SINrep(nsP2S726): a tool for rapid heterologous expression with attenuated cytotoxicity in neurons.PMID 14757348Read ↗

Alphaviruses: Semliki Forest Virus and Sindbis Virus Vectors for Gene Transfer into NeuronsSemantic proximity Read ↗

Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells.Semantic proximity Read ↗

Deletion of multiple immediate–early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neuronsSemantic proximity Read ↗

Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells: the importance of a mutation in the nsP2 gene.Semantic proximity Read ↗

Pseudo-typed Semliki Forest virus delivers EGFP into neuronsSemantic proximity Read ↗

Anterograde transneuronal tracing and genetic control with engineered yellow fever vaccine YFV-17D.Semantic proximity Read ↗

Replication of the herpes simplex virus type 1 RL1 mutant 1716 in primary neuronal cell cultures--possible relevance to use as a viral vector.Semantic proximity Read ↗

Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity.Semantic proximity Read ↗

Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.Semantic proximity Read ↗

uniSynK: a ratio-optimized bicistronic chemically induced dimerization tool for robust induction of dendritic spine enlargementSemantic proximity Read ↗

Nontoxic, double-deletion-mutant rabies viral vectors for retrograde targeting of projection neuronsSemantic proximity Read ↗

Genetic Determinants of Cell Type-Specific Poliovirus Propagation in HEK 293 CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.