Article
Novel mutant Semliki Forest virus vectors: gene expression and localization studies in neuronal cells.
Histochemistry and cell biology - 1 Jan 2001
Lundstrom K, Rotmann D, Hermann D, Schneider E M, Ehrengruber M U
Abstract excerpt
Semliki Forest virus vectors (SFV) are suitable for high-level transgene expression in neuronal tissue, both in vitro and in vivo. Cortical and hippocampal primary neurons in culture are efficiently infected resulting in 75-95% of GFP-positive cells, and injection of SFV vectors into hippocampal...
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