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Article

Prion domain interaction responsible for species discrimination in yeast [PSI+] transmission.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 2003

Hara Hideyuki, Nakayashiki Toru, Crist Colin G, Nakamura Yoshikazu

Abstract excerpt

BACKGROUND: The yeast [PSI+] factor is transmitted by a prion mechanism involving self-propagating Sup35 aggregates. As with mammalian prions, a species barrier prevents prion transmission between yeast species. The N-terminal of Sup35 of Saccharomyces cerevisiae, necessary for [PSI+], contains two species-signature elements-a Gln/Asn-rich region (residues 1-41; designated NQ) that is followed by oligopeptide...

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Identifiers

PMID: 14750948
DOI: 10.1111/j.1365-2443.2003.00694.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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