Article
Propagation of the [PIN+] prion by fragments of Rnq1 fused to GFP.
Current genetics - 1 May 2007
Vitrenko Yakov A, Pavon Mariana E, Stone Stephen I, Liebman Susan W
Abstract excerpt
Prions are viewed as enigmatic infectious entities whose genetic properties are enciphered solely in an array of self-propagating protein aggregate conformations. Rnq1, a yeast protein with yet unknown function, forms a prion named [PIN+] for its ability to facilitate the de novo induction of another prion, [PSI+]. Here we investigate a set of RNQ1 truncations that were designed to cover major Rnq1 sequence...
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