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Article

CRE-mediated transcription is increased in Huntington's disease transgenic mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jan 2004

Obrietan Karl, Hoyt Kari R

Abstract excerpt

Disruption of cAMP response element (CRE)-dependent transcription has been hypothesized to contribute to neuronal death and dysfunction in Huntington's disease (HD) and other polyglutamine repeat disorders. Whether dysregulation of CRE-dependent transcription actually occurs in vivo in response t...

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Identifiers

PMID: 14749423
DOI: 10.1523/JNEUROSCI.3493-03.2004
PMCID: PMC6729812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14749423-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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