Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activated THP-1 Cells: an Attractive Model for the Assessment of Intracellular Growth Rates ofMycobacterium tuberculosisIsolates

24 Jan 2004

Abstract excerpt

Capacity of certain Mycobacterium tuberculosis isolates to grow more rapidly in human macrophages may be indicative of increased virulence. Significant differences were observed in intracellular growth of two isolates from sites of tuberculosis transmission, with an outbreak-associated strain growing faster than a strain causing disease in only one person. Activated THP-1 cells are a suitable alternative to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diagnosis and treatment of tuberculosis
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14742569
DOI: 10.1128/iai.72.2.1169-1173.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Activated THP-1 Cells: an Attractive Model for the Assessment of Intracellular Growth Rates ofMycobacterium tuberculosisIsolatesPMID 14742569Read ↗

Differences in Rate and Variability of Intracellular Growth of a Panel ofMycobacterium tuberculosisClinical Isolates within a Human Monocyte ModelSemantic proximity Read ↗

In-depth comparison of cell-based methodological approaches to determine drug susceptibility of visceral Leishmania isolatesSemantic proximity Read ↗

Virulent clinical isolates of <i>Mycobacterium tuberculosis</i> grow rapidly and induce cellular necrosis but minimal apoptosis in murine macrophagesSemantic proximity Read ↗

Drug resistant clinical isolates of Mycobacterium tuberculosis from different genotypes exhibit differential host responses in THP-1 cells.Semantic proximity Read ↗

Comparative transcriptomics of THP-1 monocytes in response to different pathogensSemantic proximity Read ↗

Modern Lineages of Mycobacterium tuberculosis Exhibit Lineage-Specific Patterns of Growth and Cytokine Induction in Human Monocyte-Derived MacrophagesSemantic proximity Read ↗

Epidemiologic consequences of microvariation in Mycobacterium tuberculosis.Semantic proximity Read ↗

Decades Long Involvement of THP-1 Cells as a Model for Macrophage Research: A Comprehensive ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.