Article

Comparative transcriptomics of THP-1 monocytes in response to different pathogens

2017-06-26

Abstract excerpt

Undifferentiated human monocytes encounter various pathogens while present in the bloodstream. They are considered a primary responder and regulator for human immune reactions. As such, experiments investigating responses to pathogens are often reliant on monocyte cell cultures. For reproducibility reasons, immortalized cell lines are used. One of the most important cell lines used to model pathogen interactions i...

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Literature Corpus work: cea5078f-b67b-5f62-b9f4-5a1129832ad9
DOI: 10.1101/155853

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