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Article

Type III Secretion: a Virulence Factor Delivery System Essential for the Pathogenicity of Burkholderia mallei

24 Jan 2004

Abstract excerpt

By creating mutations in the Burkholderia mallei ATCC 23344 animal pathogen-like type III secretion system (TTSS), this study analyzes the correlation between type III secretion and the pathogenicity of ATCC 23344 in vivo. Mutagenesis demonstrated that a functional TTSS was required for the full pathogenicity of ATCC 23344 in the BALB/c mouse and Syrian hamster models of infection. However, vaccination with each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 14742564
DOI: 10.1128/iai.72.2.1150-1154.2004

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