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Novel Burkholderia mallei Virulence Factors Linked to Specific Host-Pathogen Protein Interactions

25 Jun 2013

Abstract excerpt

Burkholderia mallei is an infectious intracellular pathogen whose virulence and resistance to antibiotics makes it a potential bioterrorism agent. Given its genetic origin as a commensal soil organism, it is equipped with an extensive and varied set of adapted mechanisms to cope with and modulate host-cell environments. One essential virulence mechanism constitutes the specialized secretion systems that are...

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PMID: 23800426
DOI: 10.1074/mcp.m113.029041

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