Article
Complex genetics of complex traits: the case of primary open-angle glaucoma.
Clinical & experimental ophthalmology - 1 Jul 2006
Hewitt Alex W, Craig Jamie E, Mackey David A
Abstract excerpt
Glaucoma, which is a complex heterogeneous disease, presents an ideal case for genetic investigation. Primary open-angle glaucoma (POAG) is the commonest subtype and will be the focus of this review. When detected early, POAG is amenable to therapeutic intervention. Unfortunately, current population-based clinical screening lacks efficacy. If individuals with a genetic predisposition for developing POAG can be...
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