Article
Extensive gene traffic on the mammalian X chromosome.
Science (New York, N.Y.) - 23 Jan 2004
Emerson J J, Kaessmann Henrik, Betrán Esther, Long Manyuan
Abstract excerpt
Mammalian sex chromosomes have undergone profound changes since evolving from ancestral autosomes. By examining retroposed genes in the human and mouse genomes, we demonstrate that, during evolution, the mammalian X chromosome has generated and recruited a disproportionately high number of functional retroposed genes, whereas the autosomes experienced lower gene turnover. Most autosomal copies originating from...
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