Article
The evolution of gene regulatory programs controlling gonadal development in primates
2025-06-19
Abstract excerpt
Sex-determining pathways produce dimorphic gonads (ovaries and testes), yet the gene regulatory programs governing gonadogenesis and their evolution in primates remain little explored. Here we report evolutionary analyses of transcriptome and chromatin accessibility data of male and female human, marmoset (New World monkey), and mouse gonadal cells spanning key prenatal stages. We find that the two primates and mo...
Topics
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- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Renal and related cancers
- Reproductive Biology and Fertility
- Sex and Gender in Healthcare
- Sexual Differentiation and Disorders
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- c785bf94-3056-53b0-bc8e-91d5c74dbdab
- DOI
- 10.1101/2025.06.17.659946
