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Article

A codon 31ser-arg polymorphism of the WAF-1/CIP-1/p21/tumour suppressor gene in Chinese primary open-angle glaucoma.

Acta ophthalmologica Scandinavica - 1 Feb 2004

Tsai Fuu-Jen, Lin Hui-Ju, Chen Wen-Chi, Tsai Chang-Hai, Tsai Shih-Wei

Abstract excerpt

PURPOSE: Glaucomatous neuropathy is a type of cell death by apoptosis. Apoptosis is a genetically controlled form of cell death, and one of its primary regulatory steps is the activation of the tumour suppressor protein p53, of which p21 is an effector protein. The association between p21 codon 31 polymorphism and primary open-angle glaucoma (POAG) patients was evaluated in this study. METHODS: The study included...

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Identifiers

PMID: 14738489
DOI: 10.1111/j.1395-3907.2004.0180.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A codon 31ser-arg polymorphism of the WAF-1/CIP-1/p21/tumour suppressor gene in Chinese primary open-angle glaucoma.PMID 14738489Read ↗

A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians.Semantic proximity Read ↗

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No point mutation but a codon 31ser-->arg polymorphism of the WAF-1/CIP-1/p21 tumor suppressor gene in nasopharyngeal carcinoma (NPC): the polymorphism distinguishes Caucasians from Chinese.Semantic proximity Read ↗

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P21 codon 31 polymorphism associated with cancer among white people: evidence from a meta-analysis involving 78,074 subjects.Semantic proximity Read ↗

The codon 31 polymorphism of the p53-inducible gene p21 shows distinct differences between major ethnic groups.Semantic proximity Read ↗

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