Article
p21 gene codon 31 polymorphism is associated with bladder cancer.
Urologic oncology - 1 Jan 2000
Chen Wen-Chi, Wu Hsi-Chin, Hsu Cheng-Der, Chen Huey-Yi, Tsai Fuu-Jen
Abstract excerpt
The function of p21 is related to cell apoptosis, progression and malignancies. It is thought that p21 is related to cancer formation but is not related to tumor grade. We aimed to investigative the polymorphism of p21 codon 31 as a candidate for the genetic marker of bladder cancer and its progression. The distribution was analyzed in 53 bladder cancer patients, 119 healthy controls in Taiwanese patients....
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