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The C677T methylenetetrahydrofolate reductase gene mutation and nephropathy in type 2 diabetes mellitus.

Medical science monitor : international medical journal of experimental and clinical research - 1 Feb 2004

Ksiazek Piotr, Bednarek-Skublewska Anna, Buraczyńska Monika

Abstract excerpt

BACKGROUND: Diabetic nephropathy is a common cause of end-stage renal disease, responsible for about 35% of renal replacement therapy cases. The susceptibility to nephropathy is due to environmental and genetic factors and varies among individuals. Mutations of the methylenetetrahydrofolate reductase (MTHFR) gene have been shown to be associated with a predisposition to diabetic nephropathy in some populations....

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Source

Identifiers

PMID: 14737040

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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