Article
The relationship of the methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish type 2 diabetic patients with and without nephropathy.
Diabetes/metabolism research and reviews - 1 Nov 2007
Eroglu Z, Erdogan M, Tetik A, Karadeniz M, Cetinalp S, Kosova B, Gunduz C, Ozgen A G, Yilmaz C
Abstract excerpt
BACKGROUND: Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported to be correlated with hyperhomocysteinemia and the severity of coronary artery disease as macroangiopathy. We aim to investigate...
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