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Article

Methylenetetrahydrofolate reductase gene polymorphism and susceptibility to diabetic nephropathy in type 1 diabetes.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jun 2003

Makita Yuichiro, Moczulski Dariusz K, Bochenski Jacek, Smiles Adam M, Warram James H, Krolewski Andrzej S

Abstract excerpt

BACKGROUND: The T allele of the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with elevated plasma homocysteine levels, and it has been postulated to be a risk factor for the development of diabetic nephropathy. We examined this hypothesis in both a case-control and a follow-up study in individuals with type 1 diabetes. METHODS: In the case-control study, the control...

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Share to Amino Acid Substitution
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 12776270
DOI: 10.1016/s0272-6386(03)00350-0

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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