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Article

Expression of human nephrin mRNA in diabetic nephropathy

21 Jan 2004

Abstract excerpt

BACKGROUND: Diabetic nephropathy (DN) is associated with functional changes in the filtration barrier, and microalbuminuria is a strong predictor of the development of overt DN. Nephrin is a novel podocyte-specific protein which localizes at the slit diaphragm. This study examines the expression of nephrin mRNA in the kidneys of type 2 diabetics with DN. METHODS: Renal tissues were obtained from 13 type 2...

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PMID: 14736962
DOI: 10.1093/ndt/gfg545

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