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Clinical and genetic characteristics of α cardiac actin gene mutations in hypertrophic cardiomyopathy

1 Jan 2004

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a dominantly inherited disease defined by unexplained myocardial hypertrophy. The prevalence is about 0.2% in the general population. The condition is characterised by a heterogeneous disease expression, and common symptoms include angina, dyspnoea, palpitations, syncope, and exercise limitation. Hypertrophic cardiomyopathy is a frequent cause of sudden cardiac death in young...

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PMID: 14729850
DOI: 10.1136/jmg.2003.010447

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