Article
No variants in the cardiac actin gene in Finnish patients with dilated or hypertrophic cardiomyopathy.
American heart journal - 1 Jun 2002
Kärkkäinen Satu, Peuhkurinen Keijo, Jääskeläinen Pertti, Miettinen Raija, Kärkkäinen Päivi, Kuusisto Johanna, Laakso Markku
Abstract excerpt
BACKGROUND: Dilated and hypertrophic cardiomyopathies are primary myocardial diseases that cause considerable morbidity and mortality. Although these cardiomyopathies are clinically heterogeneous, genetic factors play an important role in their etiology and pathogenesis. The defects in the cardiac actin (ACTC) gene can cause both cardiomyopathies. The aim of our study was to screen for variants in the ACTC gene...
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