Article
Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction.
Clinical chemistry and laboratory medicine - 1 Jan 2006
Baum Larry, Ng Ho Keung, Wong Ka Sing, Tomlinson Brian, Rainer Timothy Hudson, Chen Xiangyan, Cheung Wing Sze, Tang Jinling, Tam Wilson Wai San, Goggins William, Tong Cindy See Wai, Chan Daniel Kam Yin, Thomas G Neil, Chook Ping, Woo Kam Sang
Abstract excerpt
BACKGROUND: Because apolipoprotein E (apoE) and lipopoprotein lipase (LPL) polymorphisms interact with each other and with other factors to affect lipid metabolism, we sought to determine their separate and combined effects in association with ischemic vascular disease. METHODS: We performed a case-control study of 816 subjects: 246 acute ischemic stroke patients, 234 acute myocardial infarction patients, and 336...
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