Article
Apolipoprotein E epsilon 2 allele and risk of stroke in the older population.
Stroke - 1 Dec 1997
Ferrucci L, Guralnik J M, Pahor M, Harris T, Corti M C, Hyman B T, Wallace R B, Havlik R J
Abstract excerpt
BACKGROUND AND PURPOSE: There is evidence for a role of apolipoprotein E (apoE) in atherosclerosis. Coronary heart disease morbidity is higher in persons carrying an epsilon 4 allele and lower in those carrying an epsilon 2 allele, but the effect on cerebrovascular disease is controversial. We estimated the risk of stroke associated with different apoE genotypes in older persons. METHODS: At the sixth annual...
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