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Article

Cumulative effect of predisposing genotypes and their interaction with modifiable factors on the risk of ischemic stroke in young adults.

Stroke - 1 Mar 2005

Pezzini Alessandro, Grassi Mario, Del Zotto Elisabetta, Archetti Silvana, Spezi Raffaella, Vergani Veronica, Assanelli Deodato, Caimi Luigi, Padovani Alessandro

Abstract excerpt

BACKGROUND AND PURPOSE: Combinations of multiple predisposing polymorphisms and their interactions with modifiable factors may result in synergistic effects on the risk of ischemic stroke. These mechanisms are more likely to play a relevant role in younger individuals. METHODS: The cumulative effect of the 20210A variant of prothrombin gene, the 1691A variant of factor V gene, the TT677 genotype of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15692115
DOI: 10.1161/01.STR.0000155741.31499.c2

Genes

APOE
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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