Article
Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes.
Blood - 1 May 2004
Epling-Burnette Pearlie Kay, Painter Jeffrey S, Chaurasia Pratima, Bai Fanqi, Wei Sheng, Djeu Julie Y, Loughran Thomas P
Abstract excerpt
The natural killer (NK) type of lymphoproliferative disease of granular lymphocytes (LDGL) is associated with the expansion of CD3(-), CD16(+), and/or CD56(+) lymphocytes. We have examined the repertoire of NK receptors expressed on these cells and delineated the functional activity. We found skewed NK receptor expression on patient NK cells. Reactivity to a single anti-killer cell immunoglobulin-like receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
