The Immunophenotypic Attributes of NK Cells and NK-Cell Lineage Lymphoproliferative Disorders

Abstract excerpt

Natural killer (NK) cells are a distinct lymphocyte subset that, like cytotoxic T cells, recognize and destroy abnormal self-cells. Unlike T cells, however, NK cells lack a uniquely rearranged antigen receptor gene or a single defining immunophenotypic attribute. Furthermore, there is considerable functional and phenotypic overlap between NK cells and cytotoxic T cells, and the latter are induced by cellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAR-T cell therapy research
• Share to Immune Cell Function and Interaction
• Share to T-cell and B-cell Immunology