Article
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis.
The Journal of biological chemistry - 26 Mar 2004
Yasui Yoshihiro, Urano Takeshi, Kawajiri Aie, Nagata Koh-ichi, Tatsuka Masaaki, Saya Hideyuki, Furukawa Koichi, Takahashi Toshitada, Izawa Ichiro, Inagaki Masaki
Abstract excerpt
Mitotic kinases regulate cell division and its checkpoints, errors of which can lead to aneuploidy or genetic instability. One of these is Aurora-B, a key kinase that is required for chromosome alignment at the metaphase plate and for cytokinesis in mammalian cells. We report here that human Auro...
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