Article
A role for yeast glutaredoxin genes in selenite-mediated oxidative stress.
Fungal genetics and biology : FG & B - 1 Aug 2008
Lewinska Anna, Bartosz Grzegorz
Abstract excerpt
Since the double Deltagrx1Deltagrx2 mutant is hypersensitive to selenite we decided to evaluate mechanisms underlying this phenomenon and establish the roles of other components of yeast glutaredoxin system, in particular glutaredoxin 5 in the selenite resistance. We found elevation in the intracellular and mitochondrial superoxide production in the Deltagrx1Deltagrx2 and Deltagrx5 mutants after Se(IV) treatment....
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