Article
Activation of EGF receptor kinase by L1-mediated homophilic cell interactions.
Molecular biology of the cell - 1 Apr 2004
Islam Rafique, Kristiansen Lars V, Romani Susana, Garcia-Alonso Luis, Hortsch Michael
Abstract excerpt
Neural cell adhesion molecules (CAMs) are important players during neurogenesis and neurite outgrowth as well as axonal fasciculation and pathfinding. Some of these developmental processes entail the activation of cellular signaling cascades. Pharmacological and genetic evidence indicates that the neurite outgrowth-promoting activity of L1-type CAMs is at least in part mediated by the stimulation of neuronal...
Topics
- Animals
- Blotting, Western
- Cell Adhesion
- Cell Communication
- Cell Line
- Drosophila
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- ErbB Receptors
- Humans
- Models, Biological
- Neural Cell Adhesion Molecule L1
- Phenotype
- Phosphorylation