Article
Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA.
Journal of molecular neuroscience : MN - 1 Jan 1992
Reid R A, Hemperly J J
Abstract excerpt
The L1 cell adhesion molecule was initially identified and characterized in mouse as a cell-surface glycoprotein that mediates neuron-neuron and neuron-Schwann cell adhesion. We have characterized L1 in humans using cDNA structural and mRNA expression analyses. We present the entire coding sequence for human L1, which predicts a 1253-amino acid protein displaying a signal sequence, transmembrane segment, RGD...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Adhesion
- Cell Adhesion Molecules, Neuronal
- DNA
- Gene Expression
- Genes
- Genetic Variation
- Humans
- Leukocyte L1 Antigen Complex
- Mice
