Association of IL4 and IL4R polymorphisms with multiple sclerosis susceptibility in Caucasian population: A meta-analysis.

doi:10.1016/j.jns.2016.02.049

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Article

Association of IL4 and IL4R polymorphisms with multiple sclerosis susceptibility in Caucasian population: A meta-analysis.

Journal of the neurological sciences - 15 Apr 2016

Zhang Zhaoqiang, Wang Lei, Sun Xiao, Zhang Li, Lu Lianyuan

Abstract excerpt

BACKGROUND: Previous studies have suggested a role for interleukin-4 (IL4) and its receptor (IL4R) gene in susceptibility to multiple sclerosis (MS), but the results remain controversial and under-powered. OBJECTIVES: To investigate the contradictory results, we performed a meta-analysis to assess the possible association between polymorphisms of the IL4 rs2243250 (C/T), variable number of tandem repeat (VNTR)...

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PMID: 27000232
DOI: 10.1016/j.jns.2016.02.049

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