Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

b-Catenin and Cyclin D1: Connecting Development to Breast Cancer

1 Feb 2004

Abstract excerpt

Beta-catenin and cyclin D1 have attracted considerable attention due to their proto-oncogenic roles in human cancer. The finding of cyclin D1 as a direct target gene of beta-catenin in colon cancer cells led to the assumption that cyclin D1 upregulation is pivotal to beta-catenin's oncogenicity. Our recent paper shows that this is not the case; cyclin D1 dampens the oncogenicity of activated beta-catenin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cancer-related Molecular Pathways
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14712077
DOI: 10.4161/cc.3.2.665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

b-Catenin and Cyclin D1: Connecting Development to Breast CancerPMID 14712077Read ↗

Cyclins and Cell Cycle Control in Cancer and DiseaseSemantic proximity Read ↗

Cyclin D1 and mammary carcinoma: new insights from transgenic mouse modelsSemantic proximity Read ↗

Correlation of Beta-Catenin and Cyclin D1 Expression in Colon CancersSemantic proximity Read ↗

An update on the implications of cyclin D1 in oral carcinogenesisSemantic proximity Read ↗

Beta-catenin and Tcfs in mammary development and cancer.Semantic proximity Read ↗

Revving the Throttle on an Oncogene: CDK8 Takes the Driver SeatSemantic proximity Read ↗

Specific protection against breast cancers by cyclin D1 ablation.Semantic proximity Read ↗

ras activity and cyclin D1 expression: An essential mechanism of mouse skin tumor developmentSemantic proximity Read ↗

Cyclin D1 and human neoplasiaSemantic proximity Read ↗

Beta-catenin: a transforming actor on many stages.Semantic proximity Read ↗

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.Semantic proximity Read ↗

Significance of E-cadherin/β-catenin complex and cyclin D1 in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.