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Article

BRCA1 and BRCA2 founder mutations and the risk of colorectal cancer.

Journal of the National Cancer Institute - 7 Jan 2004

Niell Bethany L, Rennert Gad, Bonner Joseph D, Almog Ronit, Tomsho Lynn P, Gruber Stephen B

Abstract excerpt

BACKGROUND: Mutations in BRCA1 and/or BRCA2 (BRCA1/2) profoundly increase the risks of breast and ovarian cancers, but it is unclear whether mutations in these genes increase the risk of colorectal cancer. We investigated BRCA1/2 founder mutations and a family history of breast cancer as potential risk factors for colorectal cancer. METHODS: In the population-based Molecular Epidemiology of Colorectal Cancer...

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Source

Identifiers

PMID: 14709734
DOI: 10.1093/jnci/djh008

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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