Article
BRCA1 and BRCA2 mutations and the risk for colorectal cancer.
Clinical genetics - 1 May 2015
Sopik V, Phelan C, Cybulski C, Narod S A
Abstract excerpt
Women who carry a BRCA1 or BRCA2 mutation are at high risk of breast and ovarian cancer, and may be at moderately increased risk of other cancer types. This review examines studies to date that have evaluated the risk of BRCA1 and BRCA2 mutations for colorectal cancer. Accurate knowledge of colorectal cancer risk in BRCA1/2 carriers is important, because colonoscopy screening can prevent colorectal cancer through...
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