Article
Hypermutation of HIV type 1 genomes isolated from infants soon after vertical infection.
AIDS research and human retroviruses - 1 Dec 2003
Koulinska Irene N, Chaplin Beth, Mwakagile Davis, Essex Max, Renjifo Boris
Abstract excerpt
Hypermutation involving excessive G-to-A substitutions in the dinucleotide context GA or GG is common among the lentiviruses and results in multiple stop codons across the genome. Hypermutated viruses have been associated with slower disease progression and might reflect an antiviral cell-defense...
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