Article
Molecular characterization of HIV type 1 vpu genes from mothers and infants after perinatal transmission.
AIDS research and human retroviruses - 20 Jul 2001
Yedavalli V R, Husain M, Horodner A, Ahmad N
Abstract excerpt
We compared 162 vpu sequences of human immunodeficiency virus type 1 (HIV-1) in peripheral blood mononuclear cell DNA of 6 infected mother-infant pairs after perinatal transmission, and found a 90.12% frequency of intact vpu open reading frames. The heterogeneity of vpu genes between epidemiologically linked mother-infant pairs was lower compared with epidemiologically unlinked individuals. However, the...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- Child, Preschool
- Conserved Sequence
- Female
- Genes, vpu
- Genetic Variation
- HIV Infections
- HIV-1
- Humans
- Infant
- Infant, Newborn
- Infectious Disease Transmission, Vertical
- Male
