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In vivo HIV-1 hypermutation and viral loads among antiretroviral-naive Brazilian patients.

AIDS research and human retroviruses - 1 Sept 2014

de Lima-Stein Mariana Leão, Alkmim Wagner Tadeu, Bizinoto Maria Clara de Souza, Lopez Luis Fernandez, Burattini Marcelo Nascimento, Maricato Juliana Terzi, Giron Leila, Sucupira Maria Cecília Araripe, Diaz Ricardo Sobhie, Janini Luiz Mario

Abstract excerpt

Hypermutation alludes to an excessive number of specific guanine-to-adenine (G- >A) substitutions in proviral DNA and this phenomenon is attributed to the catalytic activity of cellular APOBECs. Population studies relating hypermutation and the progression of infection by human immunodeficiency virus type 1 (HIV-1) have been performed to elucidate the effect of hypermutation on the natural course of HIV-1...

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Identifiers

PMID: 25065371
DOI: 10.1089/AID.2013.0241
PMCID: PMC4151062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vivo HIV-1 hypermutation and viral loads among antiretroviral-naive Brazilian patients.PMID 25065371Read ↗

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