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Article

HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin.

The Journal of biological chemistry - 12 Mar 2004

Xing Hongyan, Mayhew Christopher N, Cullen Katherine E, Park-Sarge Ok-Kyong, Sarge Kevin D

Abstract excerpt

Induction of heat shock protein (HSP) gene expression by stress is initiated by binding of HSF1 to HSP gene promoters to increase their transcription. The cytoprotective functions of these HSPs are essential for cell survival, and thus it is critical that inducible HSP gene expression be executed rapidly and efficiently. Here we report an interaction between heat shock factor 1 (HSF1) and symplekin, a protein...

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Identifiers

PMID: 14707147
DOI: 10.1074/jbc.M311719200

Genes

HSF1

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HSF1 modulation of Hsp70 mRNA polyadenylation via interaction with symplekin.PMID 14707147Read ↗

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