Article
A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity.
Analytical biochemistry - 1 Nov 2003
Stolworthy Tiffany S, Krabbenhoft Elizabeth, Black Margaret E
Abstract excerpt
Guanylate kinase is a critical enzyme in the biosynthesis of guanosine 5'-triphosphate (GTP) and dGTP and is responsible for the phosphorylation of guanosine 5'-monophosphate (GMP) and dGMP to guanosine 5'-diphosphate (GDP) and dGDP, respectively. As with many nucleotide-metabolizing enzymes, gua...
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